GMC2 Liquid Glucosamine for Humans

What is Glucosamine and What Are The Benefits?

Glucosamine is a substance produced naturally in the body from a sugar (glucose) and an amino acid (glutamine). As well as contributing to the formation of joint building blocks (glycosaminoglycans) needed to make cartilage, tendons, ligaments and joint fluid, it acts as a biological signal to switch on the repair of these tissues, and to suppress inflammation and the breakdown of cartilage. Its production declines with age, contributing to joint deterioration. Research suggests that supplementing a healthy diet with glucosamine could help to ease achy joints and stiffness.

Our bodies naturally make glucosamine as part of its way of keeping our joints lubricated and flexible for maximum mobility. Glucosamine is needed to react with hydrochloric acid in the stomach to eventually produce Hyaluronic Acid, which is a glycosaminoglycan. Hyaluronic acid is found naturally in cartilage, tendons, ligaments and synovial fluid around the joints. It helps with elasticity. Hyaluronic acid is unique among glycosaminoglycans in that it is nonsulfated, and can be very large, with its molecular weight often reaching the millions. It is one of the main components of the extracellular matrix. The extracellular matrix provides structural support to animal cells. The extracellular matrix is the most important feature of connective tissue in animals.

Arthritis

As some people get older they develop a degenerative condition known as osteoarthritis which is characterized by pain, stiffness, swelling of the joints and a general inability to move about easily. The condition, which is irreversible, is caused by the deterioration and eventual loss of bone cartilage, the soft connective tissue that protects joints and keeps bones from directly rubbing against each other. Some studies suggest that most people over 60 have osteoarthritis though the severity of the symptoms can vary greatly among individuals. Arthritis affects nearly 70 million Americans.

Relieving arthritis with glucosamine

Numerous allopathic and natural remedies are touted as treatments for the symptoms of osteoarthritis. Among them are nutritional supplements based on a substance called Glucosamine. Glucosamine is a naturally occurring amino sugar in the body that plays a vital role in keeping cartilage and other body tissues healthy. As people get older their bodies start producing less glucosamine. This gradual diminishing of glucosamine causes the bone cartilage to lose some of its elasticity and become stiff and inflexible, eventually resulting in osteoarthritis. Glucosamine supplements are designed to slow this process by compensating for the loss of the amino sugar that occurs with age. Glucosamine supplements are believed to help in the production of glycosaminoglycan, a molecule that helps repair and rebuild damaged cartilage.

Research

Although it has only been tracked since the early 80’s, research shows that it is generally safe for most people.
Though glucosamine along with chondroitin supplements have been fairly widely used for some time now, there is still considerable discussion about the extent of their effectiveness in treating osteoarthiritis. Previous clinical studies have suggested for instance that the effectiveness of a glucosamine supplement is dependent on whether it is a Glucosamine hydrochloride or Glucosamine Sulfate.
Glucosamine hydrocholride vs glucosamine sulfate
Some research suggests that Glucosamine sulfate is more effective at alleviating osteoarthritis symptoms because it is more bio-available, or most easily absorbed by the body compared to hydrochloride supplements. Other studies however suggest that Glucosamine hydrochloride supplements are more concentrated, and are absorbed more rapidly in the gastrointestinal tract than other Glucosamine supplements. A third school of thought holds that Glucosamine supplements are most effective only when they are taken along with chondroitin supplements.

Glucosamine/chondroitin Arthritis Intervention Trial (GAIT)
Sufferers of osteoarthritis who are looking for some clarity on the subject unfortunately have little to go by. The most solid research to date on the effectiveness of Glucosamine was conducted by the University of Utah, School of Medicine on behalf of the National Institutes of Health (NIH). The study, which was called Glucosamine/chondroitin Arthritis Intervention Trial (GAIT), was designed to test the short-term effectiveness of Glucosamine and chondroitin sulfate in reducing pain associated with osteoarthritis.
The study of 1583 patients suggested that patients with moderate to severe pain did indeed obtain statistically significant pain relief when they took Glucosamine combined with chondroitin sulfate. The results were somewhat less clear in the case of osteoarthritis suffers with only moderate pain. The NIH study however looked only at the effectiveness of Glucosamine hydrochloride supplements and not Glucosamine Sulfate based ones.
Meanwhile, a much earlier three-year clinical study conducted in the Prague Institute of Rheumatology, showed Glucosamine Sulfate to be effective in slowing the progression of knee osteoarthritis. The results of this study were very similar to those from a previous clinical study investigating the effectiveness of Glucosamine sulfate. What appears less clear though is the effectiveness of Glucosamine when it is taken by itself. The GAIT study for instance, showed that Glucosamine alone fared little better than a placebo in relieving osteoarthritis symptoms.

Where can I find a good quality form of Glucosamine?

GMC² Liquid from Osumex which is a high quality liquid glucosamine complex (hydrochloride and sulphate) containing MSM, Chondroitin, an amazing Collagen blend of bioavailable amino acids and other natural ingredients. It is formulated to soothe sore aching joints, maintain joint flexibility, stimulate cartilage growth and reduce inflammation of existing joint tissues.

MSM is a powerful anti-inflammatory and soothes the sore swollen muscles and connective tissues which are the main causes of pain. In liquid form the absorption rate is significantly higher than that of powder or tablets. It contains no artificial colouring such as blue dye, artificial sweetener such as sucralose or Spenda or any artificial flavours. Instead it uses natural grape concentrates and grape skin extract for the human version and apple and pear concentrates for the pet version. The Collagen blend of amino acids have been proven to generate faster and more effective beneficial results which will be within weeks instead of months.

GMC² is even more effective for supporting joint health and easing joint pain when used with Osumex 100% Pure Antarctic Krill Oil due to the highly bioavailability of the Omega-3 in the krill oil.

What real life users of GMC² are saying

Email from a UK User:

I don't do testimonials, but this has made my knee livable with for 3 years now.

Ask not what you did for me yesterday, what will you do for me tomorrow, they say.

Regards

Ken Lewsey

"... I do think the inflammation is coming down, at least some of the pain. Remember I have a leg torn in a bad accident and I subject my body to torture in the name of fun. This is not normal use but yet I can stand up to it and I know when off everything when I waited for the product the pain/inflammation was becoming bad, very difficult to sleep after I trained. That pain really has subsided. It must be working...

It must be working as I remember I had trouble driving home from the races because of the pain. It was nearly impossible for me to lift my knee up and down during driving. that doesn't bother me now. The pain would radiate across the lower portion of the knee and down the front of my leg. It was agony driving home. Nada now."

Ms Janis Milliken D.V.M., MS, DACVPM - June 11, 2009 - Ontario, Canada
Ms Milliken is a practising vet and a triathlon participant on a regular basis - placed first in HSBC Triathlon in pic

Krill Oil Benefits & Information

Krill Oil Benefits

Krill oil is an extract prepared from a species of antarctic krill,
Euphausia superb.Despite the relative novelty of krill oil, there is a lot
 of evidence for its benefits.

Cardiovascular health

The biggest benefit is on blood cholesterol, where multiple 
studies have shown that it raises HDL (the 'good' cholesterol) 
significantly while lowering LDL (the bad cholesterol) for a slight
reduction in total cholesterol. It also appears to lower blood
triglycerides, for an overall beneficial impact on heart disease.

Arthritis

Krill oil also appears to provide a notable reduction in C-reactive proteins
 in people suffering from rheumatoid arthritis, which helps with 
overall pain and inflammation. Studies done so far show a 30 per cent 
reduction in CRP within 30 days of beginning to take krill oil.
 One additional study shows that there is also a substantial reduction in overall 
symptoms of arthritis, but that study has not been repeated yet.

In addition to well-supported effects on cardiovascular health and arthritis, 
krill oil also seems to have some benefits for PMS symptoms, particularly 
in reducing irritability and easing overall blood flow.

How Krill Oil Works in the Body

Most people have heard plenty about the need to include omega-3 fatty acids
 in their diet for both heart and brain health, and the recommendation is usually 
to take them in the form of fish oil. What many people have not heard, though,
 is that there's a relatively new kid on the block that works even better. It's called krill oil.

Much like fish oil is made by separating out the fatty acids from the tissues of oily fish, 
krill oil is made using krill, which is a group of extremely small crustaceans.
 Krill have a similar fatty acid content to fish, with about the same levels of
 DHA (docosahexaenoic acid) and slightly more EPA (eicosapentanoic acid). 
Where krill gets its advantage, though, is in the specific form of the fatty acids.

                        

Krill oil vs fish oil

Fish oil holds its fatty acids primarily in the form of triglycerides.
 The fatty acids in krill oil, on the other hand, are bound mostly as phospholipids. 
What does this mean on a practical level? It means that the fatty acids in krill oil
 have a much higher bioavailability than the ones in fish oil. 
Simply put, your body can use a whole lot more of what's in krill oil.

In addition to the fatty acids, krill oil contains various other compounds. 
The primary ones are vitamin E, which is beneficial to blood flow and 
metabolism, and astaxanthin, which is a carotenoid that helps with eye health and
 inflammation. It is still unknown whether krill oil contains these compounds in
 high enough percentages to make an impact, but research will surely continue.

Where can I find a good Krill Oil?

Osumex Pure Antarctic Krill Oil is produced from krills harvested only
 in the pure unpolluted waters of the Antarctic Ocean.
 The producer practices safe and sustainable harvesting and 
collaborates closely with eco-watch groups such as WWF to ensure 
sustainable harvesting of the Antarctic krill and oil production.  

The Antarctic krill lives in the unpolluted coldest and most pristine 
waters on earth. It also holds very potent digestive enzymes that make
 it unsuitable for trawling because it practically self destructs very quickly 
when taken out of the water for processing. Safe and sustainable harvesting means the 
processing equipment stays under water while a continuous stream of water brings the
fresh raw krill on board the factory vessel. 

This allows for processing of fresh raw material on board the floating life science factory 
which means bioactive components are retained for superior quality. This means that the
 krill oil obtained are of the purest and highest quality without any adulteration. 
There are many krill oil products sold today where it is produced from small batches 
and multiple small sources that are pooled together to make one batch for production. 
These cannot be considered pure krill oil.

Osumex Antarctic Pure Krill Oil is rich in natural Omega-3 Fatty Acids and Astaxanthin
 a very powerful antioxidants giving the rich red colour. Due to the presence of Astaxanthin 
content which is recognized for its health-promoting free radical suppression no additives
 are required to maintain the integrity and purity of the krill oil in the vegetable soft gel capsule. 
Most fish oil supplements on the other hand require much additives to ensure viability and 
to maintain shelf-life. In addition a significant proportion of the long-chain Omega-3 
fatty acids in the krill oil is in phospholipid form. In contrast, the Omega-3 in dietary
 supplements derives from cod liver, seal and or fish oils are almost exclusively 
Omega-3 triglyceride fatty acids.

Osumex Antarctic Pure Krill Oil is safe to use with no known side effects or toxicity from
 preclinical studies and research. However, it is always recommended that you check with
 your doctor or professional health-care give before using the product.

Osumex Antarctic Pure Krill Oil is encapsulated in a vegetable soft gel cap and therefore
 does not contain gluten or gelatin from animal sources.
Warning: Contains shellfish (krill).People with shellfish allergy, coagulopathy or taking anticoagulants or 
other medications should notify their physician and be tested prior to taking dietary supplements.
 If you are pregnant or nursing, consult your physician before taking this product. Keep out of reach of children.